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High Abundance Proteins Depletion vs Low Abundance Proteins Enrichment: Comparison of Methods to Reduce the Plasma Proteome Complexity

BACKGROUND: To date, the complexity of the plasma proteome exceeds the analytical capacity of conventional approaches to isolate lower abundance proteins that may prove to be informative biomarkers. Only complex multistep separation strategies have been able to detect a substantial number of low abu...

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Detalhes bibliográficos
Main Authors: Millioni, Renato, Tolin, Serena, Puricelli, Lucia, Sbrignadello, Stefano, Fadini, Gian Paolo, Tessari, Paolo, Arrigoni, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087803/
https://ncbi.nlm.nih.gov/pubmed/21573190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019603
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