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Spiroborate esters in the borane-mediated asymmetric synthesis of pyridyl and related heterocyclic alcohols
The effectiveness of several spiroborate ester catalysts was investigated in the asymmetric borane reduction of 2-, 3-, 4-acetylpyridines under different reaction conditions. Highly enantiomerically enriched 1-(2-, 3- and 4-pyridyl)ethanols and 1-(heterocyclic)ethanols were obtained using 1 to 10% c...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948488/ https://ncbi.nlm.nih.gov/pubmed/20890455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetasy.2007.10.044 |
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