Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers

Aneuploidy is a hallmark of human cancers, but most mouse cancer models lack the extensive aneuploidy seen in many human tumors. The zebrafish is becoming an increasingly popular model for studying cancer. Here we report that malignant peripheral nerve sheath tumors (MPNSTs) that arise in zebrafish...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, GuangJun, Hoersch, Sebastian, Amsterdam, Adam, Whittaker, Charles A., Lees, Jacqueline A., Hopkins, Nancy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947874/
https://ncbi.nlm.nih.gov/pubmed/20837522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011548107
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