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Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers
Aneuploidy is a hallmark of human cancers, but most mouse cancer models lack the extensive aneuploidy seen in many human tumors. The zebrafish is becoming an increasingly popular model for studying cancer. Here we report that malignant peripheral nerve sheath tumors (MPNSTs) that arise in zebrafish...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947874/ https://ncbi.nlm.nih.gov/pubmed/20837522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011548107 |
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