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Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers

Aneuploidy is a hallmark of human cancers, but most mouse cancer models lack the extensive aneuploidy seen in many human tumors. The zebrafish is becoming an increasingly popular model for studying cancer. Here we report that malignant peripheral nerve sheath tumors (MPNSTs) that arise in zebrafish...

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Main Authors: Zhang, GuangJun, Hoersch, Sebastian, Amsterdam, Adam, Whittaker, Charles A., Lees, Jacqueline A., Hopkins, Nancy
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947874/
https://ncbi.nlm.nih.gov/pubmed/20837522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011548107
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