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Agent strain variation in human prion disease: insights from a molecular and pathological review of the National Institutes of Health series of experimentally transmitted disease

Six clinico-pathological phenotypes of sporadic Creutzfeldt–Jakob disease have been characterized which correlate at the molecular level with the type (1 or 2) of the abnormal prion protein, PrP(TSE), present in the brain and with the genotype of polymorphic (methionine or valine) codon 129 of the p...

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Bibliografiske detaljer
Main Authors: Parchi, Piero, Cescatti, Maura, Notari, Silvio, Schulz-Schaeffer, Walter J., Capellari, Sabina, Giese, Armin, Zou, Wen-Quan, Kretzschmar, Hans, Ghetti, Bernardino, Brown, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947429/
https://ncbi.nlm.nih.gov/pubmed/20823086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awq234
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