The Calreticulin-Binding Sequence of Thrombospondin 1 Regulates Collagen Expression and Organization During Tissue Remodeling

Amino acids 17-35 of the thrombospondin1 (TSP1) N-terminal domain (NTD) bind cell surface calreticulin to signal focal adhesion disassembly, cell migration, and anoikis resistance in vitro. However, the in vivo relevance of this signaling pathway has not been previously determined. We engineered loc...

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Bibliografske podrobnosti
Main Authors: Sweetwyne, Mariya T., Pallero, Manuel A., Lu, Ailing, Van Duyn Graham, Lauren, Murphy-Ullrich, Joanne E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2010
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947268/
https://ncbi.nlm.nih.gov/pubmed/20724603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090903
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