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Intracellular Calreticulin Regulates Multiple Steps in Fibrillar Collagen Expression, Trafficking, and Processing into the Extracellular Matrix

Calreticulin (CRT), a chaperone and Ca(2+) regulator, enhances wound healing, and its expression correlates with fibrosis in animal models, suggesting that CRT regulates production of the extracellular matrix. However, direct regulation of collagen matrix by CRT has not been previously demonstrated....

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Detalhes bibliográficos
Main Authors: Van Duyn Graham, Lauren, Sweetwyne, Mariya T., Pallero, Manuel A., Murphy-Ullrich, Joanne E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844156/
https://ncbi.nlm.nih.gov/pubmed/20044481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006841
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