Intracellular Calreticulin Regulates Multiple Steps in Fibrillar Collagen Expression, Trafficking, and Processing into the Extracellular Matrix

Calreticulin (CRT), a chaperone and Ca(2+) regulator, enhances wound healing, and its expression correlates with fibrosis in animal models, suggesting that CRT regulates production of the extracellular matrix. However, direct regulation of collagen matrix by CRT has not been previously demonstrated....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Van Duyn Graham, Lauren, Sweetwyne, Mariya T., Pallero, Manuel A., Murphy-Ullrich, Joanne E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Glycobiology and Extracellular Matrices
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844156/
https://ncbi.nlm.nih.gov/pubmed/20044481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006841
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