The Calreticulin-Binding Sequence of Thrombospondin 1 Regulates Collagen Expression and Organization During Tissue Remodeling

Amino acids 17-35 of the thrombospondin1 (TSP1) N-terminal domain (NTD) bind cell surface calreticulin to signal focal adhesion disassembly, cell migration, and anoikis resistance in vitro. However, the in vivo relevance of this signaling pathway has not been previously determined. We engineered loc...

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Bibliografiska uppgifter
Huvudupphovsmän: Sweetwyne, Mariya T., Pallero, Manuel A., Lu, Ailing, Van Duyn Graham, Lauren, Murphy-Ullrich, Joanne E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2010
Ämnen:
Regular Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947268/
https://ncbi.nlm.nih.gov/pubmed/20724603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090903
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