The Calreticulin-Binding Sequence of Thrombospondin 1 Regulates Collagen Expression and Organization During Tissue Remodeling

Amino acids 17-35 of the thrombospondin1 (TSP1) N-terminal domain (NTD) bind cell surface calreticulin to signal focal adhesion disassembly, cell migration, and anoikis resistance in vitro. However, the in vivo relevance of this signaling pathway has not been previously determined. We engineered loc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sweetwyne, Mariya T., Pallero, Manuel A., Lu, Ailing, Van Duyn Graham, Lauren, Murphy-Ullrich, Joanne E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2010
Pynciau:
Regular Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947268/
https://ncbi.nlm.nih.gov/pubmed/20724603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090903
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