Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation

Dense deposit disease (DDD) is a severe renal disease characterized by accumulation of electron-dense material in the mesangium and glomerular basement membrane. Previously, DDD has been associated with deficiency of factor H (fH), a plasma regulator of the alternative pathway (AP) of complement act...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Martínez-Barricarte, Rubén, Heurich, Meike, Valdes-Cañedo, Francisco, Vazquez-Martul, Eduardo, Torreira, Eva, Montes, Tamara, Tortajada, Agustín, Pinto, Sheila, Lopez-Trascasa, Margarita, Morgan, B. Paul, Llorca, Oscar, Harris, Claire L., Rodríguez de Córdoba, Santiago
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947238/
https://ncbi.nlm.nih.gov/pubmed/20852386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43343
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados