The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome

Atypical hemolytic uremic syndrome (aHUS) associates with complement dysregulation caused by mutations and polymorphisms in complement activators and regulators. However, the reasons why some mutations in complement proteins predispose to aHUS are poorly understood. Here, we have investigated the fu...

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Detaylı Bibliyografya
Yayımlandı:Mol Immunol
Asıl Yazarlar: Martínez-Barricarte, Rubén, Heurich, Meike, López-Perrote, Andrés, Tortajada, Agustin, Pinto, Sheila, López-Trascasa, Margarita, Sánchez-Corral, Pilar, Morgan, B. Paul, Llorca, Oscar, Harris, Claire L., Rodríguez de Córdoba, Santiago
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Pergamon Press 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503813/
https://ncbi.nlm.nih.gov/pubmed/25879158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2015.03.248
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