Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

Although the role of Hedgehog (Hh) signalling in embryonic pattern formation is well established1, its functions in adult tissue renewal and maintenance remain unclear, and the relationship of these functions to cancer development has not been determined. Here we show that the lossof Smoothened (Smo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhao, Chen, Chen, Alan, Jamieson, Catriona H., Fereshteh, Mark, Abrahamsson, Annelie, Blum, Jordan, Kwon, Hyog Young, Kim, Jynho, Chute, John P., Rizzieri, David, Munchhof, Michael, VanArsdale, Todd, Beachy, Philip A., Reya, Tannishtha
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946231/
https://ncbi.nlm.nih.gov/pubmed/19169242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07737
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg