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β-Arrestin2 mediates the initiation and progression of myeloid leukemia

β-Arrestins were initially discovered as negative regulators of G protein-coupled receptor signaling. Although β-arrestins have more recently been implicated as scaffold proteins that interact with various mitogenic and developmental signals, the genetic role of β-arrestins in driving oncogenesis is...

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Detalhes bibliográficos
Main Authors: Fereshteh, Mark, Ito, Takahiro, Kovacs, Jeffrey J., Zhao, Chen, Kwon, Hyog Young, Tornini, Valerie, Konuma, Takaaki, Chen, Minyong, Lefkowitz, Robert J., Reya, Tannishtha
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411976/
https://ncbi.nlm.nih.gov/pubmed/22773819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209815109
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