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Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
Although the role of Hedgehog (Hh) signalling in embryonic pattern formation is well established1, its functions in adult tissue renewal and maintenance remain unclear, and the relationship of these functions to cancer development has not been determined. Here we show that the lossof Smoothened (Smo...
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| 主要な著者: | , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946231/ https://ncbi.nlm.nih.gov/pubmed/19169242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07737 |
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