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Defective Gonadotropin-Dependent Ovarian Folliculogenesis and Granulosa Cell Gene Expression in Inhibin-Deficient Mice

Inhibin-α knockout (Inha(−/−)) female mice develop sex cord-stromal ovarian cancer with complete penetrance and previous studies demonstrate that the pituitary gonadotropins (FSH and LH) are influential modifiers of granulosa cell tumor development and progression in inhibin-deficient females. Recen...

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Autors principals: Nagaraja, Ankur K., Middlebrook, Brooke S., Rajanahally, Saneal, Myers, Michelle, Li, Qinglei, Matzuk, Martin M., Pangas, Stephanie A.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946151/
https://ncbi.nlm.nih.gov/pubmed/20739397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0428
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