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Loss of inhibin alpha uncouples oocyte-granulosa dynamics and disrupts postnatal folliculogenesis

Targeted disruption of the inhibin α gene (Inha(−/−)) in mice results in an ovarian phenotype of granulosa cell tumors that renders the animals infertile. Little is known about the reproductive defects prior to tumor development. Here, we report novel data on early follicle dynamics in Inha(−/−) mic...

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Библиографические подробности
Главные авторы: Myers, Michelle, Middlebrook, Brooke S., Matzuk, Martin M., Pangas, Stephanie A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753717/
https://ncbi.nlm.nih.gov/pubmed/19666016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.08.001
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