Defective Gonadotropin-Dependent Ovarian Folliculogenesis and Granulosa Cell Gene Expression in Inhibin-Deficient Mice

Inhibin-α knockout (Inha(−/−)) female mice develop sex cord-stromal ovarian cancer with complete penetrance and previous studies demonstrate that the pituitary gonadotropins (FSH and LH) are influential modifiers of granulosa cell tumor development and progression in inhibin-deficient females. Recen...

Full description

Saved in:
Bibliographic Details
Main Authors: Nagaraja, Ankur K., Middlebrook, Brooke S., Rajanahally, Saneal, Myers, Michelle, Li, Qinglei, Matzuk, Martin M., Pangas, Stephanie A.
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946151/
https://ncbi.nlm.nih.gov/pubmed/20739397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0428
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items