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Luteinizing hormone promotes gonadal tumorigenesis in inhibin-deficient mice
The inhibins are secreted α:β heterodimers of the TGF-β superfamily that are mainly synthesized in Sertoli cells and granulosa cells, and are critical regulators of testicular and ovarian development and function. Mice homozygous for a targeted deletion of the inhibin α subunit gene (Inha(-/-)) deve...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743404/ https://ncbi.nlm.nih.gov/pubmed/18657590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2008.06.019 |
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