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Luteinizing hormone promotes gonadal tumorigenesis in inhibin-deficient mice

The inhibins are secreted α:β heterodimers of the TGF-β superfamily that are mainly synthesized in Sertoli cells and granulosa cells, and are critical regulators of testicular and ovarian development and function. Mice homozygous for a targeted deletion of the inhibin α subunit gene (Inha(-/-)) deve...

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Detalles Bibliográficos
Autores principales: Nagaraja, Ankur K., Agno, Julio E., Kumar, T. Rajendra, Matzuk, Martin M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743404/
https://ncbi.nlm.nih.gov/pubmed/18657590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2008.06.019
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