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SVA retrotransposons: Evolution and genetic instability
SINE-VNTR-Alus (SVA) are non-autonomous hominid specific retrotransposons that are associated with disease in humans. SVAs are evolutionarily young and presumably mobilized by the LINE-1 reverse transcriptase in trans. SVAs are currently active and may impact the host through a variety of mechanisms...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945828/ https://ncbi.nlm.nih.gov/pubmed/20416380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2010.04.001 |
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