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SVA Elements Are Nonautonomous Retrotransposons that Cause Disease in Humans

L1 elements are the only active autonomous retrotransposons in the human genome. The nonautonomous Alu elements, as well as processed pseudogenes, are retrotransposed by the L1 retrotransposition proteins working in trans. Here, we describe another repetitive sequence in the human genome, the SVA el...

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Bibliografske podrobnosti
Main Authors: Ostertag, Eric M., Goodier, John L., Zhang, Yue, Kazazian Jr., Haig H.
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Human Genetics 2003
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180407/
https://ncbi.nlm.nih.gov/pubmed/14628287
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