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NOD2 and TLR2 function independently in a murine model of arthritis triggered by intra-articular peptidoglycan

OBJECTIVE: Blau syndrome is an autoinflammatory disease resulting from mutations in NOD2 (nucleotide-binding oligomerization domain 2), wherein granulomatous arthritis, uveitis and dermatitis develop. The mechanisms by which aberrant NOD2 causes joint inflammation are poorly understood. Indeed very...

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Bibliografski detalji
Glavni autori: Rosenzweig, Holly L., Jann, Monica J., Vance, Emily E., Planck, Stephen. R., Rosenbaum, James T., Davey, Michael P.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945367/
https://ncbi.nlm.nih.gov/pubmed/20131263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27335
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