Activation of nucleotide oligomerization domain 2 exacerbates a murine model of proteoglycan-induced arthritis

In addition to its role in innate immunity, nucleotide oligomerization domain 2 (NOD2) has been shown to play a suppressive role in models of colitis. Notably, mutations in NOD2 cause the inherited granulomatous disease of the joints called Blau syndrome, thereby linking NOD2 with joint disease as w...

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Détails bibliographiques
Auteurs principaux: Rosenzweig, H. L., Jann, M. M., Glant, T. T., Martin, T. M., Planck, S. R., van Eden, W., van Kooten, P. J. S., Flavell, R. A., Kobayashi, K. S., Rosenbaum, J. T., Davey, M. P.
Format: Artigo
Langue:Inglês
Publié: The Society for Leukocyte Biology 2009
Sujets:
Host Defense and Pathophysiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718807/
https://ncbi.nlm.nih.gov/pubmed/19129483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0808478
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