Nucleotide Oligomerization Domain-2 Interacts with 2’-5’- Oligoadenylate Synthetase Type 2 and Enhances RNase-L Function in THP-1 Cells

Nucleotide-binding and oligomerization domain 2 (NOD2) is an intracellular a protein involved in innate immunity and linked to chronic inflammatory diseases in humans. Further characterization of the full spectrum of proteins capable of binding to NOD2 may provide new insights into its normal functi...

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Hauptverfasser: Dugan, Jae W., Albor, Amador, David, Larry, Fowlkes, Jonathan, Blackledge, Marc T., Martin, Tammy M., Planck, Stephen R., Rosenzweig, Holly L., Rosenbaum, James T., Davey, Michael P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787966/
https://ncbi.nlm.nih.gov/pubmed/19853919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.09.025
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