Activating Transcription Factor 3 regulates in part the enhanced tumour cell cytotoxicity of the histone deacetylase inhibitor M344 and cisplatin in combination

BACKGROUND: Activating Transcription Factor (ATF) 3 is a key regulator of the cellular integrated stress response whose expression has also been correlated with pro-apoptotic activities in tumour cell models. Combination treatments with chemotherapeutic drugs, such as cisplatin, and histone deacetyl...

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Bibliographic Details
Main Authors: St Germain, Carly, O'Brien, Anna, Dimitroulakos, Jim
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Primary Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945341/
https://ncbi.nlm.nih.gov/pubmed/20828393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-10-32
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