Cisplatin Induces Cytotoxicity through the Mitogen-Activated Protein Kinase Pathways and Activating Transcription Factor 3

The mechanisms underlying the proapoptotic effect of the chemotherapeutic agent, cisplatin, are largely undefined. Understanding the mechanisms regulating cisplatin cytotoxicity may uncover strategies to enhance the efficacy of this important therapeutic agent. This study evaluates the role of activ...

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Autores principales: St. Germain, Carly, Niknejad, Nima, Ma, Laurie, Garbuio, Kyla, Hai, Tsonwin, Dimitroulakos, Jim
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907579/
https://ncbi.nlm.nih.gov/pubmed/20651982
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