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Cisplatin Induces Cytotoxicity through the Mitogen-Activated Protein Kinase Pathways and Activating Transcription Factor 3

The mechanisms underlying the proapoptotic effect of the chemotherapeutic agent, cisplatin, are largely undefined. Understanding the mechanisms regulating cisplatin cytotoxicity may uncover strategies to enhance the efficacy of this important therapeutic agent. This study evaluates the role of activ...

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Détails bibliographiques
Auteurs principaux: St. Germain, Carly, Niknejad, Nima, Ma, Laurie, Garbuio, Kyla, Hai, Tsonwin, Dimitroulakos, Jim
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press Inc. 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907579/
https://ncbi.nlm.nih.gov/pubmed/20651982
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