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Cisplatin Induces Cytotoxicity through the Mitogen-Activated Protein Kinase Pathways and Activating Transcription Factor 3

The mechanisms underlying the proapoptotic effect of the chemotherapeutic agent, cisplatin, are largely undefined. Understanding the mechanisms regulating cisplatin cytotoxicity may uncover strategies to enhance the efficacy of this important therapeutic agent. This study evaluates the role of activ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: St. Germain, Carly, Niknejad, Nima, Ma, Laurie, Garbuio, Kyla, Hai, Tsonwin, Dimitroulakos, Jim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907579/
https://ncbi.nlm.nih.gov/pubmed/20651982
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