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Cisplatin Induces Cytotoxicity through the Mitogen-Activated Protein Kinase Pathways and Activating Transcription Factor 3

The mechanisms underlying the proapoptotic effect of the chemotherapeutic agent, cisplatin, are largely undefined. Understanding the mechanisms regulating cisplatin cytotoxicity may uncover strategies to enhance the efficacy of this important therapeutic agent. This study evaluates the role of activ...

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Autori principali: St. Germain, Carly, Niknejad, Nima, Ma, Laurie, Garbuio, Kyla, Hai, Tsonwin, Dimitroulakos, Jim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907579/
https://ncbi.nlm.nih.gov/pubmed/20651982
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