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Induction of Indoleamine 2,3 Dioxygenase-1 by Immunostimulatory-DNA Limits Severity of Experimental Colitis

The chronic inflammatory bowel diseases are characterized by aberrant innate and adaptive immune responses to commensal luminal bacteria. In both human IBD and in experimental models of colitis there is an increased expression of the enzyme indoleamine 2,3 dioxygenase (IDO). IDO expression has the c...

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Détails bibliographiques
Auteurs principaux: Ciorba, Matthew A, Bettonville, Ellen E, McDonald, Keely G, Metz, Richard, Prendergast, George C, Newberry, Rodney D, Stenson, William F
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945286/
https://ncbi.nlm.nih.gov/pubmed/20181893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900291
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