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Induction of Indoleamine 2,3 Dioxygenase-1 by Immunostimulatory-DNA Limits Severity of Experimental Colitis

The chronic inflammatory bowel diseases are characterized by aberrant innate and adaptive immune responses to commensal luminal bacteria. In both human IBD and in experimental models of colitis there is an increased expression of the enzyme indoleamine 2,3 dioxygenase (IDO). IDO expression has the c...

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Main Authors: Ciorba, Matthew A, Bettonville, Ellen E, McDonald, Keely G, Metz, Richard, Prendergast, George C, Newberry, Rodney D, Stenson, William F
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945286/
https://ncbi.nlm.nih.gov/pubmed/20181893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900291
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