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Induction of Indoleamine 2,3 Dioxygenase-1 by Immunostimulatory-DNA Limits Severity of Experimental Colitis

The chronic inflammatory bowel diseases are characterized by aberrant innate and adaptive immune responses to commensal luminal bacteria. In both human IBD and in experimental models of colitis there is an increased expression of the enzyme indoleamine 2,3 dioxygenase (IDO). IDO expression has the c...

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Bibliografiske detaljer
Main Authors: Ciorba, Matthew A, Bettonville, Ellen E, McDonald, Keely G, Metz, Richard, Prendergast, George C, Newberry, Rodney D, Stenson, William F
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945286/
https://ncbi.nlm.nih.gov/pubmed/20181893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900291
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