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Induction of Indoleamine 2,3 Dioxygenase-1 by Immunostimulatory-DNA Limits Severity of Experimental Colitis

The chronic inflammatory bowel diseases are characterized by aberrant innate and adaptive immune responses to commensal luminal bacteria. In both human IBD and in experimental models of colitis there is an increased expression of the enzyme indoleamine 2,3 dioxygenase (IDO). IDO expression has the c...

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Detalhes bibliográficos
Main Authors: Ciorba, Matthew A, Bettonville, Ellen E, McDonald, Keely G, Metz, Richard, Prendergast, George C, Newberry, Rodney D, Stenson, William F
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945286/
https://ncbi.nlm.nih.gov/pubmed/20181893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900291
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