TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

MicroRNAs (miRNAs) are generated by a two-step processing pathway to yield RNA molecules of approximately 22 nucleotides that negatively regulate target gene expression at the post-transcriptional level1. Primary miRNAs are processed to precursor miRNAs (pre-miRNAs) by the Microprocessor complex2–4....

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Bibliografiset tiedot
Päätekijät: Chendrimada, Thimmaiah P., Gregory, Richard I., Kumaraswamy, Easwari, Norman, Jessica, Cooch, Neil, Nishikura, Kazuko, Shiekhattar, Ramin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2005
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944926/
https://ncbi.nlm.nih.gov/pubmed/15973356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03868
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