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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
MicroRNAs (miRNAs) are generated by a two-step processing pathway to yield RNA molecules of approximately 22 nucleotides that negatively regulate target gene expression at the post-transcriptional level1. Primary miRNAs are processed to precursor miRNAs (pre-miRNAs) by the Microprocessor complex2–4....
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944926/ https://ncbi.nlm.nih.gov/pubmed/15973356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03868 |
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