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ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing

Adenosine deaminases acting on RNA (ADARs) are involved in RNA editing that converts adenosine residues to inosine specifically in double-stranded RNAs. In this study, we investigated the interaction of the RNA editing mechanism with the RNA interference (RNAi) machinery and found that ADAR1 forms a...

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Hlavní autoři: Ota, Hiromitsu, Sakurai, Masayuki, Gupta, Ravi, Valente, Louis, Wulff, Bjorn-Erik, Ariyoshi, Kentaro, Iizasa, Hisashi, Davuluri, Ramana V., Nishikura, Kazuko
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651894/
https://ncbi.nlm.nih.gov/pubmed/23622242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.03.024
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