Chargement en cours...
ADAR1 RNA editing enzyme regulates R-loop formation and genome stability at telomeres in cancer cells
ADAR1 is involved in adenosine-to-inosine RNA editing. The cytoplasmic ADAR1p150 edits 3’UTR double-stranded RNAs and thereby suppresses induction of interferons. Loss of this ADAR1p150 function underlies the embryonic lethality of Adar1 null mice, pathogenesis of the severe autoimmune disease Aicar...
Enregistré dans:
| Publié dans: | Nat Commun |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7955049/ https://ncbi.nlm.nih.gov/pubmed/33712600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21921-x |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|