Llwytho...
ADAR1 RNA editing enzyme regulates R-loop formation and genome stability at telomeres in cancer cells
ADAR1 is involved in adenosine-to-inosine RNA editing. The cytoplasmic ADAR1p150 edits 3’UTR double-stranded RNAs and thereby suppresses induction of interferons. Loss of this ADAR1p150 function underlies the embryonic lethality of Adar1 null mice, pathogenesis of the severe autoimmune disease Aicar...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Commun |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group UK
2021
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7955049/ https://ncbi.nlm.nih.gov/pubmed/33712600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21921-x |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|