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No Evidence for Induction of ABC Transporters in Peripheral Blood Mononuclear Cells in Humans after 14 Days of Efavirenz Treatment

Intracellular concentrations of antiretroviral drugs in peripheral blood mononuclear cells (PBMCs) are an important determinant of therapeutic success. In vitro data indicate that efavirenz induces several ATP-binding cassette (ABC) transporters, and pharmacogenetic studies found an association betw...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Burhenne, Jürgen, Matthée, Anne-Kathrin, Pasáková, Ivana, Röder, Claudia, Heinrich, Tilman, Haefeli, Walter Emil, Mikus, Gerd, Weiss, Johanna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944620/
https://ncbi.nlm.nih.gov/pubmed/20660679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00283-10
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