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No Evidence for Induction of ABC Transporters in Peripheral Blood Mononuclear Cells in Humans after 14 Days of Efavirenz Treatment

Intracellular concentrations of antiretroviral drugs in peripheral blood mononuclear cells (PBMCs) are an important determinant of therapeutic success. In vitro data indicate that efavirenz induces several ATP-binding cassette (ABC) transporters, and pharmacogenetic studies found an association betw...

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Detalhes bibliográficos
Main Authors: Burhenne, Jürgen, Matthée, Anne-Kathrin, Pasáková, Ivana, Röder, Claudia, Heinrich, Tilman, Haefeli, Walter Emil, Mikus, Gerd, Weiss, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944620/
https://ncbi.nlm.nih.gov/pubmed/20660679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00283-10
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