No Evidence for Induction of ABC Transporters in Peripheral Blood Mononuclear Cells in Humans after 14 Days of Efavirenz Treatment

Intracellular concentrations of antiretroviral drugs in peripheral blood mononuclear cells (PBMCs) are an important determinant of therapeutic success. In vitro data indicate that efavirenz induces several ATP-binding cassette (ABC) transporters, and pharmacogenetic studies found an association betw...

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Bibliografski detalji
Glavni autori: Burhenne, Jürgen, Matthée, Anne-Kathrin, Pasáková, Ivana, Röder, Claudia, Heinrich, Tilman, Haefeli, Walter Emil, Mikus, Gerd, Weiss, Johanna
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Antiviral Agents
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944620/
https://ncbi.nlm.nih.gov/pubmed/20660679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00283-10
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