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Combination of Tenofovir and Emtricitabine plus Efavirenz: In Vitro Modulation of ABC Transporter and Intracellular Drug Accumulation

Efflux proteins have been shown to greatly affect the uptake of antiretroviral drugs by cells and to hamper their access to the human immunodeficiency virus type 1 replication site. This study evaluated the factors that may lead to drug-drug interactions between emtricitabine (FTC), tenofovir (TFV),...

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Detalhes bibliográficos
Main Authors: Bousquet, Laurence, Pruvost, Alain, Guyot, Anne-Cécile, Farinotti, Robert, Mabondzo, Aloïse
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650525/
https://ncbi.nlm.nih.gov/pubmed/19075072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00733-08
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