Effects of Tuberculosis, Race, and Human Gene SLCO1B1 Polymorphisms on Rifampin Concentrations

Rifampin has concentration-dependent activity against Mycobacterium tuberculosis. However, marked intersubject variation of rifampin concentrations occurs. In this study, we evaluated rifampin pharmacokinetics in relation to tuberculosis, geographic region, race, and single nucleotide polymorphisms...

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Hlavní autoři: Weiner, Marc, Peloquin, Charles, Burman, William, Luo, Chi-Cheng, Engle, Melissa, Prihoda, Thomas J., Mac Kenzie, William R., Bliven-Sizemore, Erin, Johnson, John L., Vernon, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944564/
https://ncbi.nlm.nih.gov/pubmed/20660695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00353-10
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