Effects of Tuberculosis, Race, and Human Gene SLCO1B1 Polymorphisms on Rifampin Concentrations

Rifampin has concentration-dependent activity against Mycobacterium tuberculosis. However, marked intersubject variation of rifampin concentrations occurs. In this study, we evaluated rifampin pharmacokinetics in relation to tuberculosis, geographic region, race, and single nucleotide polymorphisms...

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Detalhes bibliográficos
Main Authors: Weiner, Marc, Peloquin, Charles, Burman, William, Luo, Chi-Cheng, Engle, Melissa, Prihoda, Thomas J., Mac Kenzie, William R., Bliven-Sizemore, Erin, Johnson, John L., Vernon, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944564/
https://ncbi.nlm.nih.gov/pubmed/20660695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00353-10
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