Decreased plasma rifapentine concentrations associated with AADAC single nucleotide polymorphism in adults with tuberculosis

BACKGROUND: Rifapentine exposure is associated with bactericidal activity against Mycobacterium tuberculosis, but high interindividual variation in plasma concentrations is encountered. OBJECTIVES: To investigate a genomic association with interindividual variation of rifapentine exposure, SNPs of s...

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Bibliografische gegevens
Gepubliceerd in:J Antimicrob Chemother
Hoofdauteurs: Weiner, Marc, Gelfond, Jon, Johnson-Pais, Teresa L, Engle, Melissa, Johnson, John L, Whitworth, William C, Bliven-Sizemore, Erin, Nsubuga, Pheona, Dorman, Susan E, Savic, Rada
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879139/
https://ncbi.nlm.nih.gov/pubmed/33374006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa490
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