Effects of Rifampin and Multidrug Resistance Gene Polymorphism on Concentrations of Moxifloxacin

Treatment regimens combining moxifloxacin and rifampin for drug-susceptible tuberculosis are being studied intensively. However, rifampin induces enzymes that transport and metabolize moxifloxacin. We evaluated the effect of rifampin and the human multidrug resistance gene (MDR1) C3435T polymorphism...

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Main Authors: Weiner, Marc, Burman, William, Luo, Chi-Cheng, Peloquin, Charles A., Engle, Melissa, Goldberg, Stefan, Agarwal, Vipin, Vernon, Andrew
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2007
主題:
Clinical Therapeutics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932492/
https://ncbi.nlm.nih.gov/pubmed/17517835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01621-06
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