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ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery
Accurate response to replication arrest is crucial to preserve genome stability and requires both the ATR and ATM functions. The Werner syndrome protein (WRN) is implicated in the recovery of stalled replication forks, and although an ATR/ATM-dependent phosphorylation of WRN was observed after repli...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944071/ https://ncbi.nlm.nih.gov/pubmed/20802463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.205 |
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