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WRNIP1: A new guardian of genome integrity at stalled replication forks

Failure to protect and/or restart stalled replication forks contributes to genomic instability. Radiation-sensitive 51 (RAD51) recombinase defends stalled forks from nucleolytic attack, which otherwise can threaten their integrity. Recently, we have uncovered a novel and key function of Werner helic...

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Détails bibliographiques
Publié dans:Mol Cell Oncol
Auteurs principaux: Leuzzi, Giuseppe, Marabitti, Veronica, Pichierri, Pietro, Franchitto, Annapaola
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068177/
https://ncbi.nlm.nih.gov/pubmed/27857978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1215777
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