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Discrete TCR repertoires and CDR3 features distinguish effector and Foxp3(+) regulatory T lymphocytes in MOG-EAE

Regulatory T lymphocytes (Treg) expressing the Forkhead Box Transcription Factor 3 (Foxp3) are critical modulators of autoimmunity. Foxp3(+) Treg may develop in the thymus as a population distinct from conventional Foxp3(−) αβ T cells (Tconv). Alternatively, plasticity in Foxp3 expression may allow...

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Bibliografiske detaljer
Main Authors: Nguyen, Phuong, Liu, Wei, Ma, Jing, Manirarora, Jean N., Liu, Xin, Cheng, Cheng, Geiger, Terrence L.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944006/
https://ncbi.nlm.nih.gov/pubmed/20810983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001550
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