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Intratumoral Convergence of the TCR Repertoires of Effector and Foxp3(+) CD4(+) T cells

The presence of Foxp3(+) regulatory CD4(+) T cells in tumor lesions is considered one of the major causes of ineffective immune response in cancer. It is not clear whether intratumoral T(reg) cells represent T(reg) cells pre-existing in healthy mice, or arise from tumor-specific effector CD4(+) T ce...

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Main Authors: Kuczma, Michal, Kopij, Magdalena, Pawlikowska, Iwona, Wang, Cong-Yi, Rempala, Grzegorz A., Kraj, Piotr
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964305/
https://ncbi.nlm.nih.gov/pubmed/21049016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013623
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