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Intratumoral Convergence of the TCR Repertoires of Effector and Foxp3(+) CD4(+) T cells
The presence of Foxp3(+) regulatory CD4(+) T cells in tumor lesions is considered one of the major causes of ineffective immune response in cancer. It is not clear whether intratumoral T(reg) cells represent T(reg) cells pre-existing in healthy mice, or arise from tumor-specific effector CD4(+) T ce...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964305/ https://ncbi.nlm.nih.gov/pubmed/21049016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013623 |
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